What Is Nolvadex?
Nolvadex (tamoxifen citrate) is a nonsteroidal antiestrogen used to treat breast cancer that has spread to other parts of the body (metastatic breast cancer), to treat breast cancer in certain patients after surgery and radiation therapy, and to reduce the chances of breast cancer in high-risk patients.
What Are Side Effects of Nolvadex?
Common side effects of Nolvadex include:
hot flashes,
flushing,
changes in menstrual periods,
nausea,
leg cramps,
abdominal cramps,
bone pain,
muscle pain,
cough,
swelling,
fatigue,
hair thinning,
headache,
depression, and
loss of sexual ability/interest (in men).
Tell your doctor if you have unlikely but serious side effects of Nolvadex including:
vision changes (e.g., blurred vision),
eye pain,
easy bruising or bleeding,
mental/mood changes,
swelling of ankles or feet, or
unusual tiredness.
Dosage for Nolvadex
The recommended daily dose of Nolvadex for patients with breast cancer is 20-40 mg per day, in tablet form.
What Drugs, Substances, or Supplements Interact with Nolvadex?
Nolvadex may interact with coumarin-type anticoagulants, anastrozole, letrozole, rifampin, aminoglutethimide, phenobarbital, rifampin, bromocriptine, SSRI antidepressants, and cimeditdine. Tell your doctor all medications and supplements you use.
Nolvadex During Pregnancy and Breastfeeding
There may be risks to the fetus if Nolvadex is taken by pregnant women, however the benefit of the drug may warrant its use despite the potential risks. Nolvadex has been reported to inhibit lactation. It is not known whether the medication is passed through breast milk, but because of the potential risks for the fetus, women who are taking Nolvadex should not breast feed.
Additional Information
Our Nolvadex Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
How to use Nolvadex Tablet
Read the Medication Guide provided by your pharmacist before you start using tamoxifen and each time you get a refill. If you have any questions, consult your doctor or pharmacist.
Take this medication by mouth with or without food as directed by your doctor, usually once or twice daily for 5 years. Daily dosages greater than 20 milligrams are usually divided in half and taken twice a day, in the morning and evening, or as directed by your doctor. If you are using the liquid, measure the dose carefully using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.
Dosage is based on your medical condition and response to treatment. The duration of treatment to prevent cancer from returning may be between 5 to 10 years, depending on your medical condition and response to treatment.
Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.
If you have breast cancer that has spread to other parts of the body, you may experience increased bone/cancer pain and/or disease flare-up as you start taking tamoxifen. In some cases, this may be a sign of a good response to the medication. Symptoms include increased bone pain, increased tumor size, or even new tumors. These symptoms usually disappear quickly. Always tell your doctor right away about these symptoms.
Since this drug can be absorbed through the skin and lungs, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the tablets. (See also Precautions section.)
Inform your doctor right away if your condition worsens (such as you get new breast lumps).
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