Nolvadex 10mg*100/bottle Finished Tablets

What NOLVADEX is for

NOLVADEX is used to either treat breast cancer or reduce the risk of breast cancer occurring if you are at increased risk of breast cancer.

If you and your healthcare professional are considering using NOLVADEX for reducing the risk of breast cancer occurring, your knowledge of treatment risks becomes more important because you don't currently have breast cancer. NOLVADEX therapy may be uncommonly associated with serious side effects such as deep vein thrombosis (DVT - blood clots in veins of your leg), pulmonary embolus (blood clots in your lungs) and uterine cancer. In some women, these events were fatal. Less serious side effects such as hot flushes, vaginal discharge, menstrual irregularities and gynaecological conditions may also occur. Whether the benefits of treatment outweigh the risks depends on your age, health history, your level of breast cancer risk and on your personal judgement. NOLVADEX therapy to reduce the risk of breast cancer may not be appropriate for all women at increased risk for breast cancer. An assessment with your healthcare professional of the potential benefits and risks prior to starting therapy for reduction in breast cancer risk is essential. You should understand that NOLVADEX reduces, but does not eliminate, the risk of breast cancer.

NOLVADEX blocks the actions of oestrogen. Oestrogen is a natural female sex hormone. In some types of breast cancer, oestrogen can help cancer cells to grow.

Your doctor will have explained why you are being treated with NOLVADEX and told you what dose to take.

Follow all directions given to you by your doctor.

They may differ from the information contained in this leaflet.

Your doctor may prescribe this medicine for another use. Ask your doctor if you want more information.

NOLVADEX is not addictive.

Before you use NOLVADEX

When you must not use it

Do not use NOLVADEX if you are pregnant, trying to become pregnant or are breastfeeding. We do not know if it is safe for you to take it while you are pregnant. It may affect your baby if you take it at any time during pregnancy.

Your baby may take in NOLVADEX from breast milk if you are breastfeeding.

Do not use NOLVADEX if you are allergic to tamoxifen or any of the other ingredients in NOLVADEX.

Do not use NOLVADEX for reducing the risk of breast cancer occurrence if:

you are taking medicines used to prevent blood clots such as warfarin

you have had deep vein thrombosis (DVT - blood clots in veins of your leg) or pulmonary embolus (blood clots in your lungs).

Do not give NOLVADEX to children.

There is no experience of its use in children.

Do not take after the use by (expiry) date printed on the pack.

It may have no effect at all, or worse, an entirely unexpected effect if you take it after the expiry date.

Do not take NOLVADEX if the packaging is torn or shows signs of tampering.

Do not use it to treat any other complaints unless your doctor tells you to.

Do not give this medicine to anyone else, even if they have the same condition as you.

Before you start to use it

You must tell your doctor if:

1. you have any allergies to:

tamoxifen, the active ingredient in NOLVADEX

any of the other ingredients in NOLVADEX listed at the end of this leaflet

other anti-oestrogen medicines

any other medicines

any other substances, such as foods, preservatives or dyes.

If you have an allergic reaction, you may experience a skin rash, hay fever, difficulty breathing or feel faint.

2. you have or have ever had any of these medical conditions:

a history of hereditary angioedema (as NOLVADEX may cause or worsen symptoms of hereditary angioedema).

any unexplained vaginal bleeding

problems with your blood

liver problems

deep vein thrombosis (DVT - blood clots in veins of your leg) or pulmonary embolus (blood clots in your lungs).

It may not be safe for you to take NOLVADEX if you have any of these conditions.