Sarms Finished Tablets/Capsules
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High-quality products, guaranteed shipping, and competitive prices
GiantSteroid Pharma Co., Ltd., established in June 2008, is a pilot enterprise of pharmaceutical raw materials in Shandong Province, China. We offer high-quality steroid raw materials (over 99.6% purity), HGH, HCG, SARMS, and peptides.
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High quality and competitive prices
Standard: BP/USP/EP/Enterprise standard. All purity ≥99%. As manufacturers, we can provide high-quality products at factory prices.
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Professional packaging and shipping team. Special methods to ship 100 grams to 100 kilograms of powder to your country at once. Fast and discreet shipment can be arranged to ensure customs clearance. Tracking codes available 24 hours to ensure customs clearance. Various shipping methods are also available according to your requirements.
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We have stock, and parcels can be shipped within 24 hours after payment. Tracking numbers available. Secure and discreet shipment. Various transportation methods for your choice. Customs pass rate ≥99%. We have our own agents/remailers/distributors who can help us ship our products very fast and safely, and we have stock available for transfer.
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Professional service and rich experience make customers feel at ease. Adequate stock and fast delivery meet their desires. Market feedback and goods feedback will be appreciated, meeting customers' requirements is our responsibility. High quality, competitive prices, fast delivery, gain the trust and praise from customers.
YK11
- Description: YK11 stands out as a mighty SARM , working as a partial agonist of the androgen receptor (AR) by targeting specific genes, such as myostatin (GDF8), by increasing the synthesis of follistatin (FST), enhancing its potential in promoting muscle growth and bone tissue development.
- Downside: In summary, our study identifies important pathways of YK11's hippocampal effects, revealing its potential to promote oxidative stress and mitochondrial dysfunction, suggesting that the administration of YK11 may pose potential neurological risks for athletes and bodybuilders seeking to enhance performance.
- Mechanism: YK-11 is reported to show results within a few weeks of starting a cycle, with users often noticing improvements in muscle strength and size. However, individual experiences can vary, and the full extent of its effects may become more evident over the course of a complete cycle, typically lasting 4 to 8 weeks.
- Functions: As expected, no intact YK11 was observed in the elimination study urine samples. While the unconjugated metabolites disappeared within 24 hours post-administration, both glucuronidated and sulfated metabolites were traceable for more than 48 hours.
GW501516
- Description: GW501516, also known as GW-1516 or cardarine and endurobol, is a peroxisome proliferator-activated receptor delta (PPAR-δ) agonist. Activation of the receptor will increase fat-burning capacity and muscle production, as it changes the body's fuel preference from glucose to lipids.
- Benefits: Due to Cardarine's potential role in fat burning, some athletes consider using it to get a leaner physique as well as improve their energy metabolism and cardiovascular performance. Some users claim that it boosts stamina, endurance, workout capacity, and fat loss within a few days.
- Functions: GW501516, as a potent agonist of PPARδ, regulates glycometabolism, fatty acid metabolism and insulin resistance . GW501516 has been shown to enhance the β-oxidation of liver fatty acids by increasing the expression of PPARα-target genes involved in fatty acid oxidation .
- Instructions: Commonly, the following strategies are used for Cardarine: On-Cycle: This is when you take Cardarine regularly for a set period, usually 4-12 weeks. Off-Cycle: After your on-cycle, you give your body a break from Cardarine for an equal or longer time before starting another cycle.
- Precautions: Cardarine is usually run for 6 weeks if used with SARMs like Ostarine (a popular cutting stack). If used alone however, there is no real 'rule' as to how long it can be run.
Andarine
- Description: Andarine is a selective androgen receptor modulator (SARM) that is used to help build muscle and burn fat. It is often used by bodybuilders and athletes to help increase muscle mass and strength, while also helping to reduce body fat.
- Downside: The primary side effects reported with Andarine are altered vision (i.e., yellow-tinged) and suppression of testosterone.
- Benefits: Andarin can significantly increase levels of lean muscle mass while lowering levels of body fat and increasing vascularity to give the "chiseled", sharp look that all bodybuilders strive for. The strength increase is also worth noting.
- Instructions: Both SARMs are detectable in urine for approximately 2 weeks after a single dose of 60 mg of andarine and 30 mg of ostarine.
AICAR
- Description: In skeletal muscle cells, AICAr was found to activate glycogen phosphorylase and increase glycogenolysis, stimulate fatty acid oxidation and glucose uptake, and inhibit protein synthesis .
- Functions: The adenosine monophosphate analogue 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) activates AMP-dependent protein kinase (AMPK), which is a key regulator of energy metabolism and thus a potential target for treatment of obesity-related complications .
- Mechanism: AICAR transformylase activity. ATIC catalyzes the final two steps of the formation of the first purine, IMP. In the penultimate step, the AICAR transformylase domain catalyzes the transfer of a formyl group from N10-fTHF to the 5-amino group of AICAR to yield FAICAR and THF (Fig. 3A).
MK-677
- Description: By stimulating the release of GH and insulin-like growth factor 1 (IGF-1), MK-677 helps increase protein synthesis, which is essential for building lean muscle mass. Users often report improved muscle fullness, increased strength, and enhanced workout performance when incorporating MK-677 into their fitness regimens.
- Functions: Ibutamoren begins to take effect rapidly. Upon ingestion, it leads to a significant and swift increase in growth hormone (GH) levels. Typically, by the end of the first week, noticeable changes in body composition can already be observed.
- Precautions: Unlike traditional anabolic steroids, MK-677 is considered safer and does not suppress natural hormone production, making it a promising option for muscle growth without major side effects. The usual recommended dosage range for MK-677 is between 10-25 mg per day, typically administered once daily.
MK-2866
- Description: MK-2866 leverages its anabolic effects on muscle tissue, aiding not only in treating muscle wasting diseases but also benefitting athletes aiming to build muscle. It aids in lessening degeneration during recovery from surgeries or similar situations.
- Benefits: Ostarine is a very popular anabolic SARM, making it a go-to option for people looking to grow muscle mass fast without using any kinds of steroids. If you try bulking the conventional way, it adds a bit of body fat to your build.
- Downside: CONCLUSION. Among muscle-building amateur athletes, SARMs (ligandrol or ostarine) and/or substances in PCT may cause cholestatic liver injury with prolonged recovery.
RAD140
- Description: Studies have shown that RAD-140 can increase lean muscle mass, improve strength, and support fat loss. Research also indicates potential neuroprotective effects of RAD-140. This could prove beneficial in treating neurodegenerative diseases.
- Functions: Nonsteroidal selective androgen receptor modulators (SARMs), including RAD-140, Enobosarm, and Ligandrol, promote anabolic effects on bones and muscles through binding to androgen receptors, similar to traditional anabolic-androgenic steroids such as testosterone.
- Advantage: RAD 140 is a very strong SARM, and it is considerably more anabolic than testosterone. This implies that it is very efficient at promoting growth of muscles. RAD 140 is also famous for its potential to boost bone density and improve athletic performance.
- Downside: Although there were no histological features of acute alcoholic hepatitis in the liver biopsy, alcohol use may have predisposed the patient to RAD-140- and LGD-4033-associated drug-induced liver injury. In conclusion, we reported severe drug-induced hepatotoxicity associated with RAD-140 and LGD-4033.
- Benefits: Users of RAD 140 often report seeing an increase in lean muscle mass. What's exciting about RAD 140 is that it doesn't just puff up your muscles with water weight; the gains you're getting are solid and can contribute significantly to your overall physique.
SR9009
- Description: SR9009 Stenabolic has earned a reputation in the fitness and bodybuilding world as an incredibly powerful tool for boosting endurance, increasing metabolism, and creating enhanced physical prowess.
- Advantage: SR9009, an agonist of NR1D1, augments testosterone production in TM3 cells. Knock-down of Nr1d1 represses testosterone production in TM3 cells.
- Functions: SR9009 specifically targets REV-ERB, a family of nuclear receptors that regulate the circadian clock. The researchers showed that activating REV-ERB with SR9009 in mice lowered the production of NLRP3, when they administered the drug after conventional heart attack treatments.
- Mechanism: SR9009's role as a REV-ERB antagonist means that it seems to have a strong impact on metabolism. This 2012 study found that diet-induced obese mice lost significant fat mass when given SR9009. This finding suggests that Stenabolic may be beneficial in treating metabolic diseases and help reduce fat storage in the body.
FAQ
Q: Does YK11 boost testosterone?
A: However, YK-11 is a steroidal SARM, meaning that it will effect and suppress natural testosterone levels, do it's high binding affinity for the androgen receptor.
Q: is yk11 a steroid？
A: YK-11 is a type of Selective Androgen Receptor Modulator (SARM), which is a class of compounds that are designed to mimic the effects of anabolic steroids while minimizing their negative side effects. YK-11 is often marketed as a SARM, but it is technically not a SARM, but a myostatin inhibitor.
Q: Is it safe to take YK11?
A: The long-term health effects of YK-11 are still largely unknown. Users should be aware of the potential risks that come with using a relatively untested compound. The legal status of YK-11 varies by region, and it's not approved by regulatory bodies like the FDA for medical use.
Q: What are the gains on YK11?
A: YK-11 increases protein kinase B enzyme activation. It may lead to strengthened bones and reduced fragility. Users of YK-11 also report strength gains and improved endurance, further contributing to the increase in lean muscle mass.
Q: Why does YK11 suppress testosterone?
A: However, YK-11 is a steroidal SARM, meaning that it will effect and suppress natural testosterone levels, do it's high binding affinity for the androgen receptor.
Q: Is SARMs a steroid?
A: No. SARMs are not the same as anabolic steroids. SARMs target the same receptor (chemical binding site) in your body as anabolic steroids, but they work in a more specific way. Anabolic steroids can affect all parts of the body, while SARMs target specific places — such as muscles or bones.
Q: Is YK11 a strong SARM?
A: YK11 stands out as a mighty SARM, working as a partial agonist of the androgen receptor (AR) by targeting specific genes, such as myostatin (GDF8), by increasing the synthesis of follistatin (FST), enhancing its potential in promoting muscle growth and bone tissue development.
Q: How long is YK11 detectable?
A: As expected, no intact YK11 was observed in the elimination study urine samples. While the unconjugated metabolites disappeared within 24 hours post-administration, both glucuronidated and sulfated metabolites were traceable for more than 48 hours.
Q: Do you need pct after YK11?
A: At higher doses, some people may notice testosterone drop using YK-11 so please be careful if you are new to using it, don't assume you won't need PCT.
Q: What is the best PCT after YK11?
A: SARMS PCT-EX Clomedex is recommended after using Myanabol YK-11, Ostarine MK-2866, Testolone RAD-140 and Ligandrol LGD-4033.
Q: What is the best SARM?
A: What are the Best SARMs on the Market: Top SARM Supplements to Bulk, Cut, and Muscle Gain?
Testol 140 – The strongest SARM for increasing muscle mass and raw power. ...
Ibuta 677 – Boosts growth hormone dramatically for rapid lean muscle gains. ...
Osta 2866 – Clean strength and size gains without bloating or water retention.
Testol 140 – The strongest SARM for increasing muscle mass and raw power. ...
Ibuta 677 – Boosts growth hormone dramatically for rapid lean muscle gains. ...
Osta 2866 – Clean strength and size gains without bloating or water retention.
Q: How safe is Cardarine?
A: Cardarine is on the WADA prohibited list. the toxicity of a substance: Cardarine is associated with a higher rate of numerous cancers and a high frequency of reproductive toxic effects in preclinical settings. Toxicity has been evaluated in long-term animal studies, showing an increase in tumour formation.
Q: Is 10mg Cardarine enough?
A: As little as 10mg per day is an effective dosage for Cardarine. We would suggest starting as low as possible for your first cycle and not exceeding the range given by the specific brand you are using.
Q: Will I gain muscle on cardarine?
A: Cardarine is a powerful supplement that can help burn fat, build muscle, and increase energy. However, it is crucial to comprehend the right dosage and cycle of Cardarine to get the maximum outcomes effectively and quickly.
Q: Is Cardarine muscle sparing?
A: Cardarine is a class of 'new' substances called SARMS. Unlike steroids, or prohormones, these new compounds are designed to specifically target muscle development, or at the very least keep you from losing muscle when you diet.
Q: Is GW501516 illegal?
A: Since January 2009, the list of prohibited substances and methods of doping as established by the World Anti-Doping Agency includes GW-501516, first as a gene doping substance and now in the S4. 5 Metabolic modulators class. It is prohibited at all times.
Q: Does GW501516 affect liver?
A: GW501516, as a potent agonist of PPARδ, regulates glycometabolism, fatty acid metabolism and insulin resistance . GW501516 has been shown to enhance the β-oxidation of liver fatty acids by increasing the expression of PPARα-target genes involved in fatty acid oxidation.
Q: Is AICAR a peptide?
A: According to research, AICAR is a small peptide that significantly functions in energy balance and metabolic pathways.
Q: Is AICAR a drug?
A: AICAR is an analog of adenosine monophosphate (AMP) that is capable of stimulating AMP-dependent protein kinase (AMPK) activity. The drug has also been shown as a potential treatment for diabetes by increasing the metabolic activity of tissues by changing the physical composition of muscle.
Q: What drug activates AMPK?
A: Two of the most widely used medicines in the world, metformin18, the mostly commonly used drug for type 2 diabetes, and salicylate19, the active ingredient in aspirin and salsalate, also activate AMPK, suggesting that some of their beneficial effects may be mediated in part by AMPK.
Q: What are the concerns about the availability of AICAR?
A: In recent years, AICAR has been in the news a number of times as a novel substance athletes have turned to for performance enhancement. However, this substance is both prohibited in sport and a health risk because it's not approved for therapeutic use in humans anywhere in the world.
Q: Is AMPK an enzyme?
A: AMP-activated protein kinase (AMPK) is a phylogenetically conserved fuel-sensing enzyme that is present in all mammalian cells.
Q: Is AMPK activated by insulin?
A: AMPK activity is increased by glucose deprivation of muscle cells, which correlates with increased glucose uptake and glycolysis independently of insulin.
Q: Is AMPK catabolic or anabolic?
A: The effect of AMPK activation is to rewire metabolism to decrease anabolic processes (that is, ATP consumption) and increase catabolism (that is, ATP production) to restore a more favourable energy balance.
Q: Is AMPK activated by ATP?
A: AMP-activated protein kinase (AMPK) is a conserved sensor of cellular energy change and is activated by increased AMP/ATP and/or ADP/ATP ratios.
Q: Is AMPK a protein?
A: AMPK is a heterotrimeric protein consisting of a catalytic α and regulatory β and γ subunits (3–5) (Figure 1). Each α and β subunit is encoded by 2 genes (α1 and α2 or β1 and β2), whereas the γ subunit is encoded by 3 genes (γ1, γ2, and γ3).
Q: Is AMPK in the mitochondria?
A: Herein, we demonstrate that specific isoforms of the cellular bioenergetic sensor, 5' AMP-activated protein kinase (AMPKα1/α2/β2/γ1), are localized on the outer mitochondrial membrane, referred to as mitoAMPK, in various tissues in mice and humans.
Q: Is AMPK in the liver?
A: Activation of AMPK in the liver leads to the stimulation of fatty acid oxidation and inhibition of lipogenesis, glucose production and protein synthesis.
Q: Is SR9009 good for your liver?
A: SR9009 is effective in suppressing clinical markers of liver damage, circulating lipids, hepatic fibrosis and markers of inflammation.
Q: What to stack MK-677 with?
A: How To Use RAD 140 And MK 677 Stack: For optimal results, you should take between 20 to 30mg of MK677 and between 10 to 20mg of RAD 140 every single day. You should do this for a duration of 8 to 10 weeks. Following the cycle, conduct post-cycle therapy for four to six weeks before giving the stack another run.
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