Letrozole
CAS:112809-51-5
MF:C17H11N5
MW:285.3
Synonyms:LetrozoleUsp28;Letrozole99%;CGS-20267, Femara;LETRAZOLE;letrozolex;Lelrozol;1-[BIS(4-CYANOPHENYL)METHYL]-1,2,4-TRIAZOLE;4,4'-(1H-1,2,4-Triazol-1-ylmethylene)dibenzonitrile
Description
Letrozol is an anti-estrogen of the Aromatase Inhibitor family and is one of the most potent and powerfully effective of all AI's.It was first developed in an effort to combat breast cancer in post-menopausal women.Letrozol is an oral aromatase inhibitor which is a non-steroidal drug. Letrozol treats hormonally responsive breast cancer after the surgery in females past menopause. It belongs to the class of drugs known as Aromatase inhibitors and Hormones antineoplastics.It acts by decreasing the quantity of estrogen synthesized in the body.And it is one of the most commonly used anti-estrogens among steroid users during steroid use to combat possible estrogenic related side effects. It is so effective as an anti-estrogen in this regard many anabolic steroids have effectively reversed gynecomastia symptoms with Letrozol.
COA
| Tests | Specifications | Results |
| Appearance | White or off-white crystaline powder | White Crystalline powder |
| Solubility | Soluble in ethanol when heated |
Conform |
| ldentification | (1)Maximum absorption in wavelength of 240 nm Minimum absorption in wavelength of 215 nm |
Conform Conform |
| (2)Infrared spectrum should be in accordance the dominant peak of contrast | In accordance with the dominant peak of contrast | |
| Melting points | 182ºC-184ºC | 182ºC |
| Related substances | ≤0.5% | 0.3% |
| Single impurity | ≤0.3% | 0.2% |
| Loss on drying | ≤1.0% | 0.8% |
| [Assay]C17H11N5 (On anhydrous basis) |
≥98.0% | 99.2% |
| Conclusion | Conforms Specifications of Enterprise Standard. | |
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