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Description
S4 (Andarine), like Ostarine, Ligandrol, etc., is an orally available, non-steroidal selective androgen receptor modulator (SARM).
The name says it all: SARMs act selectively-that is, only in a tissue-specific manner-at the androgen receptor. Therefore, they have no or hardly any side effects, especially compared to anabolic steroids or prohormones. Nevertheless, since they have a very strong effect in terms of muscle building, fat burning, performance enhancement and strength building, they have become increasingly popular in the sports scene.
Andarine was originally developed in medicine to treat conditions such as muscle wasting, osteoporosis, and prostatic hypertrophy (an excessive, benign enlargement of the prostate). Scientists have been able to find that Andarine acts selectively on anabolic organs such as muscle and bone, whereas it stimulates androgenic organs such as the prostate significantly less. At the same time, it does not inhibit the production of LH (luteinizing hormone) and FSH (follicle-stimulating hormone), nor does it increase estrogen synthesis. That is why the SARM S4 has become so popular with bodybuilders.


Clinical Data
Trade names Andarine S4,Acetamidoxolutamide; Androxolutamide; GTx-007; S-4 CAS
401900-40-1
Molar mass
389.334
MF
C19H18F3N3O6
Purity
Above 98%
Apprarance
White crystalline powder
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Effect Andarine (S4)
As already mentioned, Andarine increases muscle growth and bone mass without significantly affecting the prostate or natural hormone levels (especially the luteinizing hormone LSH and the follicle-stimulating hormone FSH). It is also particularly encouraging that S4 does not increase aromatase – the conversion of testosterone to estrogen. So there are few, if any, side effects.
The SARM S4 also appears to be 100 percent bioavailable. This means that the amount you take will be available in the target tissues – muscles and bones, etc.
Andarine does not bind as strongly to the testosterone receptor as, for example, Ostarine. The gains in muscle mass are solid nonetheless. Experiments showed that S4 exhibited similar anabolic effects to low doses of testosterone. In addition to more muscle mass, users were also able to build more strength. However, most users use Andarine for diet phases for fat loss because the SARM inhibits LPL (lipoprotein lipase). This is an enzyme that is responsible for the storage of fat in the tissues.
Benefits of the SARMs S4 at a glance:
Increases muscle growth or inhibits muscle breakdown
builds strength
provides reduction of body fat (inhibits LPL)
dry, hard look
no subcutaneous water retention
improves bone mass
more energy and well-being
increased vascularity
No or hardly any side effects (no enlargement of the prostate, no increased estrogen synthesis or influence on hormone levels)
to 100% bioavailable
Andarine side effects
f the dosage is too high (50 milligrams per day), the body's own testosterone production may be inhibited. In addition, slight visual disturbances – especially at night – may occur temporarily. Both side effects subside after stopping S4.
A Post-Cycle Therapy after the andarine cycle is always advisable.
Andarine (S4) Experience
Since there are no final scientific studies on the effect of S4 yet, we asked users about their experiences with Andarine. Some S4 users said the effect was very similar to Anavar.
Most strength athletes used the SARM during the diet phase to lose more fat, get a dry look, and at the same time maintain or build muscle mass. The muscle gains were less than with, for example, Ostarine. However, this is not what the SARM is intended for. Andarine mainly ensures that users can maintain muscle mass during the diet. Therefore, they were also pleased with small gains in muscle and strength. Most users were extremely satisfied with the amount of body fat lost.
None of the users reported any unpleasant side effects. Very few described worsened vision at night. Many users made the experience that their joints and bones felt more stable and resilient. In addition, almost all users were pleased that there was little or no subcutaneous water retention. Almost all stated that their appearance was significantly drier, more defined, and more muscular. Vascularity (visibility of veins) also increased.
Actually all users reported more energy and a better general well-being.
Is Andarine The Best SARM For Me?
Andarine's composition is specifically tailored to target androgen receptors, making it an exceptional fat-loss supplement. When contemplating Andarine, aligning its properties with your fitness goals is vital. To start with, think about what your biggest priorities are before you start purchasing SARMs.
Before making that decision, ask yourself the following questions:
Do you want to increase your stamina?
Are you trying to lose fat and look great for the summer or a trip?
Do you want to build muscle and gain strength?
Using Andarine in combination with other SARMs can potentially elevate performance and recovery post-strenuous activities. The compound's inherent qualities for pumping up the body and its potential for endurance enhancement make it a favourite for those looking to improve their body composition. When added to a dedicated regimen, Andarine can become an invaluable asset for anyone looking to tap into their muscle-building potential and enhance athletic performance.
When trying to build muscle and pump up the body, adhering to Andarine dosage guidelines is crucial. To ensure safe usage, consult a healthcare expert, especially regarding dosages and potential post-cycle therapy. Always weigh its benefits against potential risks.
How To Use It – Andarine Dosage
Andarine (S4) is a selective androgen receptor modulator (SARM) that is commonly used in bodybuilding and fitness for its ability to promote lean muscle growth, fat loss, and improve strength, without some of the severe side effects associated with traditional anabolic steroids. Here's a general guide on how to use Andarine and the recommended dosage. However, always consult with a healthcare provider before using any performance-enhancing substances.
Andarine Dosage
The optimal dosage of Andarine depends on your goals, experience with SARMs, and tolerance. Here's a typical breakdown:
1. Beginner Dosage (First-Time Users)
Dose: 25 mg per day
Duration: 6–8 weeks
This is a conservative starting dose for those new to SARMs or Andarine. It allows you to assess your body's response and minimize the risk of side effects.
2. Intermediate Dosage
Dose: 50 mg per day
Duration: 6–8 weeks
After assessing your tolerance, you can increase the dose to 50 mg per day. This is the most common dosage used by those who have experience with SARMs.
3. Advanced Dosage
Dose: 75 mg per day
Duration: 6–8 weeks
Advanced users may go up to 75 mg per day, though this higher dose should be used cautiously and monitored for any side effects.
How to Take Andarine
Oral Administration: Andarine is available in oral form (liquid or capsules). It is typically taken once or twice a day.
Split Dosing: Due to Andarine's relatively short half-life of about 4–6 hours, it is recommended to split the daily dosage into two equal doses (morning and evening) to maintain stable blood levels throughout the day.
With or Without Food: You can take Andarine with or without food. However, some users find that taking it with food may reduce any potential stomach discomfort.
Cycle Duration
Cycle Length: 6 to 8 weeks is generally recommended. Prolonged use beyond 8 weeks increases the risk of side effects, including suppression of natural testosterone levels.
Off-Cycle: After completing a cycle of Andarine, it's advisable to take at least 4–8 weeks off to allow your body to recover and reset.
Post-Cycle Therapy (PCT)
Although Andarine is a SARM and typically doesn't cause as much suppression of natural testosterone production as anabolic steroids, it can still suppress testosterone to a degree.
Some users may choose to use Post Cycle Therapy (PCT) after their cycle to help restore normal hormone levels and optimize recovery. Common PCT drugs include Nolvadex or Clomid.
A typical PCT for Andarine might last 4–6 weeks, depending on the individual response.
Potential Side Effects
While Andarine is considered to have a relatively mild side effect profile compared to anabolic steroids, it still carries some risks:
Visual Disturbances: One of the most common and notable side effects of Andarine is its potential impact on vision, often described as yellow-tinted vision or difficulty adjusting to low-light conditions. This is a temporary effect that goes away after stopping the compound.
Testosterone Suppression: Although Andarine is less suppressive than other SARMs or steroids, it can still suppress natural testosterone production, especially at higher doses. This is why post-cycle therapy (PCT) is recommended.
Other Effects: Potential side effects may include headaches, nausea, or mild fatigue, though these are less common.
Tips for Using Andarine Safely
Monitor Your Health: Regularly monitor your health while using Andarine, including liver function, testosterone levels, and general well-being. It's always important to track any negative side effects.
Start with a Lower Dose: If you're new to SARMs, start with the lower dose to assess your tolerance before increasing it.
Stay Hydrated and Maintain a Healthy Diet: Like any supplement or performance-enhancing substance, ensure you maintain proper hydration and nutrition while cycling Andarine.
Avoid Long Cycles: Prolonged use of Andarine can increase the likelihood of side effects. Stick to a 6–8 week cycle and take adequate time off to recover.
Legality
Andarine (S4) is classified as a research chemical and is not approved for human consumption or use by regulatory agencies like the FDA. Be aware of the legal status of SARMs in your country or region before acquiring or using Andarine.
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