Product Name: Clomifene citrate:
Product Details:
CAS:50-41-9
Name:Clomifene citrate
Formula:C26H28ClNO.C6H8O7
Molecular Weight:598.08
Synonyms:
Chloramiphene;Clomifene citrate (JP14);Clomivid;Ethanamine;Clomphid;MRL 41;Fertyl;Clomiphene dihydrogen citrate;Ikaclomin;Fertivet;Dyneric;Triethylamine, citrate;MER 41;clomifen dihydrogen citrate
EINECS:200-035-3
Melting Point:116.5-118 °C
Boiling Point:509 °C at 760 mmHg
Flash Point:261.6 °C
Appearance:crystalline solid
Assay: 99%
Package: packaged in foil bags
Storage: Cool dry place, avoid heat and direct sunlight
Application: Chemicals
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Clomifene Citrate Description:
Clomifene citrate, also known as clomiphene citrate, is a medication commonly prescribed in reproductive medicine, particularly for managing female infertility and addressing certain hormonal imbalances. Below are some of the main uses for clomifene citrate:
Uses of Clomifene Citrate:
Ovulation Induction:
Clomifene citrate is frequently used to stimulate ovulation in women who struggle with irregular or absent ovulation (anovulation). It works by increasing the secretion of hormones like follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which are crucial for stimulating the growth and release of mature eggs from the ovaries.
Polycystic Ovary Syndrome (PCOS):
Women with PCOS often face irregular or absent ovulation due to hormonal imbalances. Clomifene citrate can help regulate ovulation in such cases, improving the chances of conception by normalizing hormonal levels.
Unexplained Infertility:
In cases where infertility is present without a clear cause, clomifene citrate is often used as a first-line treatment. It helps promote ovulation and improves the likelihood of pregnancy, even when no specific infertility diagnosis is identified.
Controlled Ovarian Hyperstimulation (COH):
Clomifene citrate can be part of assisted reproductive techniques like intrauterine insemination (IUI) or in vitro fertilization (IVF). When used in combination with other medications, it can help stimulate the development of multiple follicles, increasing the chances of successful fertilization and pregnancy.
Luteal Phase Support:
In some cases, clomifene citrate is used to support the luteal phase of the menstrual cycle, which is the period between ovulation and menstruation. This support helps create a more favorable environment for embryo implantation, improving the chances of early pregnancy.
Clomifene citrate plays a vital role in assisting women with fertility challenges, offering a therapeutic option for various reproductive conditions.
Clomifene Citrate Usage :
Typically, users of clomiphene citrate will maintain daily doses between 25mg to 150mg, adjusting based on their recovery needs. Some users may begin with a higher "front-loading" dose, usually ranging from 200mg to 300mg on the first day of post-cycle therapy (PCT), before gradually reducing the dosage for the remaining duration. However, it's important to note that higher doses, especially at the beginning, can lead to increased side effects, which may make it challenging for some users to sustain these higher doses.
The general recommendation for the length of clomiphene citrate therapy is at least 3 weeks, though this can vary depending on individual recovery timelines and preferences. Factors such as the compounds used during the cycle, their duration, and the individual's metabolism will also play a role in determining the necessary length of PCT. For some, a longer or shorter course of therapy may be required, tailored to their specific needs and recovery pace.
COA :
| Tests | Analysis Standard | Results |
| Identification | Conform | Conform |
| Absorbance | ≤0.30% | Conform |
| Specific Rotation | +39°~ +43° | +39.5° |
| Chromatography Purity | Conform | Conform |
| 17α-Isomer | ≤0.50% | 0.40% |
| Organic Volatile Impurities | Conform | Conform |
| Loss On Drying | ≤0.50% | 0.32% |
| Residue On Ignition | ≤0.10% | 0.01% |
| Assay | 97~101% | 99.02% |
| Conclusion |
Be Conform With USP31 Standard |
|
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