High Purity Peptides CJC1295 With DAC

Description

CJC-1295 is a synthetic GHRH (growth hormone releasing hormone) analogue made up of 30 amino acids. It has been found to be highly effective with regards to the increase of growth hormone secretion and IGF-1 without negatively affecting the pulsatility of GH secretion.

CJC-1295 is often combined with Ipamorelin due to its enhanced specificity as a GHRH. This peptide generates similar increases in growth hormone secretion, but without the appetite stimulation and increase in cortisol, acetylcholine, prolactin, and aldosterone seen with other peptides in its class. This peptide has been found to be very well-tolerated and perfect when combined with Ipamorelin.

How does CJC1295 with DAC work?

CJC-1295 with DAC (Drug Affinity Complex) is a synthetic peptide that acts as a growth hormone-releasing hormone (GHRH) analog. Its primary function is to stimulate the pituitary gland to increase the secretion of growth hormone (GH), which indirectly raises insulin-like growth factor-1 (IGF-1) levels in the body. 

1. Binding to Growth Hormone Receptors

CJC-1295 mimics the natural GHRH by binding to specific receptors on the pituitary gland, triggering the release of stored growth hormone into the bloodstream.

2. Enhanced Half-Life with DAC

The addition of DAC increases the peptide's half-life significantly compared to traditional GHRH.

The DAC complex binds to albumin (a protein in the blood), which protects the peptide from rapid degradation and provides a steady release over several days.

3. Pulsatile Growth Hormone Release

CJC-1295 with DAC promotes pulsatile (episodic) GH release rather than continuous secretion, which mimics the body's natural growth hormone rhythm.

This pattern helps prevent receptor desensitization and maximizes the benefits of growth hormone release.

4. Increased IGF-1 Production

Higher GH levels stimulate the liver to produce IGF-1, a hormone critical for growth, repair, and metabolic functions. IGF-1 is responsible for many of the anabolic effects attributed to growth hormone.

5. Long-Lasting Effects

Due to its extended half-life (up to 8-10 days), CJC-1295 with DAC requires less frequent administration (e.g., weekly or biweekly).

What are the benefits of CJC1295 with DAC?

CJC-1295 with DAC (Drug Affinity Complex) offers a range of benefits by increasing the body's natural production of growth hormone (GH) and insulin-like growth factor-1 (IGF-1). These effects make it popular among bodybuilders, athletes, and those seeking anti-aging solutions. 

1. Muscle Growth and Strength

Enhanced protein synthesis, promoting muscle repair and growth by increasing IGF-1 levels.

Improved recovery times after intense workouts or injuries.

Lean muscle gains, helping to build quality muscle mass over time.

2. Fat Loss

Increased lipolysis, stimulating the breakdown of fat stores for energy.

Reduced body fat, promoting a leaner physique by burning excess fat, especially around the abdomen.

3. Improved Skin and Anti-Aging

Boosts collagen production, reducing wrinkles and improving skin texture.

Slows down signs of aging by supporting cellular repair and regeneration.

4. Enhanced Sleep and Recovery

Improves sleep quality, essential for growth hormone production and recovery.

Accelerates tissue repair, supporting muscles, tendons, and ligaments during rest.

5. Increased Energy and Stamina

Better endurance, supporting higher energy levels for sustained physical activity.

Improved metabolism, enhancing metabolic rate for more efficient energy use.

6. Strengthened Immune System

Helps the body recover from illness or injury more effectively.

Enhances immune function through better tissue repair and renewal.

7. Long-Lasting Effects

Due to its extended half-life (up to 8–10 days), CJC-1295 with DAC offers sustained growth hormone release, reducing the need for frequent administration.

8. Joint and Bone Health

Promotes bone density and reduces the risk of fractures.

Aids in joint repair and reduces discomfort from wear and tear.

ConjuChem and The Development of CJC-1295 + DAC

CJC-1295 + DAC is a tetrasubstituted peptide analogue of Growth Hormone Releasing Hormones with D-Ala, Gln, Ala, and Leu substitutions at positions 2, 8, 15, and 27. A Canadian biotechnology company called ConjuChem had invented CJC-1295. Clinical Research on CJC-1295 first began during the mid-2000s. The goal of the peptide, acting to raise HGH like Ipamorelin, was to treat visceral fat deposits in obese AIDS patients because it is presumed that increased levels of exogenous hgH increase fat loss, or lipolysis.

In one study, results showed that the measured GH release in rats over a two hour period showed that CJC-1295 released twice as much GH as CJC-1293 + DAC. This result makes it preferable for immediate effectiveness as a result of the longer peak. With the use of a Growth Hormone Releasing Peptide (GHRP), such as Growth Hormone Releasing Hexapeptide (GHRP-6) in conjuction with CJC-1295 + DAC, a study has shown that the GHRP's create a Growth Hormone pulse which helps the CJC-1295 work effectively. Clinical research's involving CJC-1295 have shown that it had been successful for most research subjects.

Overview

The reduction of fat mass by using the fat as an energy source. It may lead to an increased muscle mass via promoting the synthesis of proteins.
Since growth hormone promotes bone growth and improved joint and connective tissue health, CJC-1295 peptide may potentially improve bone mass and reduce injuries.
Studies have suggested that GHRH supports normalized sleep patterns, potentially this action may be extended to analogues like CJC-1295.

Research and Clinical Studies

CJC-1295 DAC Peptide Mechanism of Action
Researchers conducted two clinical studies in 2006 to examine the action of CJC-1295. The test subjects were between the ages of 21-61 years old. In the first study the CJC-1295 or placebo was presented in one of four ascending concentrations. On the other side, in the second study CJC-1295 was presented two or three times each week. According to the results, after the presentation of CJC-1295, there appeared to be an increase in GH and IGF-I levels (IGF-1: Insulin-like growth factor 1) among the subjects.

In 2006, another group of scientists assessed the GH pulsatility after a single occurrance of CJC-1295. They found out that there appeared to be an increase of about 50% in GH secretion and IGF-I levels after the single presentation of CJC-1295

CJC-1295 DAC Peptide Half-life

In its original form, CJC-1295 uses a technology referred to as Drug Affinity Complex (DAC). Contrary to the GHRH which has a half-life of approximately 7 minutes, CJC-1295 is reported by researchers to exhibit a longer half-life of 6-8 days due to the DAC technology.

CJC-1295 DAC Peptide Ancillary Studies

In 2005, a study began to evaluate the mechanism of action of CJC-1295 in subjects with immunodeficiency virus (HIV) associated with visceral obesity. In this study, the subjects would be presented with CJC-1295 for 3 months and followed by a 6 week follow-up period. However, this study was terminated during the recruitment process, and no related results were posted.

According to a Norwegian study, in 2009 a compound was submitted for analysis to evaluate whether it contained prohibited substances or not. The researchers of the Norwegian Doping Control Laboratory and School of Pharmacy reported that this substance was CJC-1295. In their published article they concluded that "CJC-1295 is a releasing factor for growth hormone".

Our Advantages

1.Quality:every item is strictly tested by our professional staff and get ISO certificate.
2.Price: much lower than our peers since we are factory. A discount would be given when you make a large order.
3.Delivery: We have adequate stock so we can make the delivery within 24 hours after payment.
4.Perfect Reshipping policy has been made to protect customers max bennefits and reduce the potentical losses.
5.Good after-sale service: always keeping track on the status of your parcel until delivered and trying our utmost to solve customers problems entounered
6.main products:Raw steroids,human growth hormone,Semi-finished oils,bodybuilding peptides,SARMs raws,Anabolic steroids