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Description

The main mechanism of action of Cialis involves the inhibition of the PDE5 enzyme. In the presence of sexual stimulation, the release of nitric oxide in the erectile tissue of the penis leads to the activation of an enzyme called guanylate cyclase. Guanylate cyclase increases the levels of cyclic guanosine monophosphate (cGMP), which relaxes the smooth muscles in the penile blood vessels, allowing increased blood flow into the penis. This increased blood flow results in an erection.

PDE5 is an enzyme that breaks down cGMP, reducing the amount available for maintaining an erection. By inhibiting PDE5, Cialis prolongs the effects of cGMP, making it easier for men with ED to achieve and maintain an erection during sexual activity.

Cialis relaxes muscles of the blood vessels and increases blood flow to particular areas of the body.

Cialis is used to treat erectile dysfunction (impotence) and symptoms of benign prostatic hypertrophy (enlarged prostate).

Another brand of tadalafil is Adcirca, which is used to treat pulmonary arterial hypertension and improve exercise capacity in men and women. Do not take Cialis while also taking Adcirca, unless your doctor tells you to.

What Is Cialis Used For?

Cialis is used to treat men with erectile dysfunction (sometimes called impotence) when they cannot get, or keep, a hard penis (erection) sufficient for satisfactory sexual activity. For Cialis to be effective in this condition, sexual stimulation is required.

Cialis can also be used in men to treat the signs and symptoms of benign prostatic hyperplasia(enlarged prostate gland that is not cancerous), which involve problems with the flow of urine.

How Is Cialis Used?

For treating erectile dysfunction, the recommended dose of Cialis is 10 mg taken 'on demand' at least 30 minutes before sexual activity. The dose may be increased to 20 mg for men who do not respond to the 10 mg dose. The maximum recommended dosing frequency is once per day, but continuous daily use of 10 or 20 mg Cialis is not recommended.

Cialis can be used at a lower dose once a day in men who intend to use it frequently (twice a week or more), based on the doctor's judgement. The dose is 5 mg once a day, but can be lowered to 2.5 mg once a day depending on how well it is tolerated. The medicine should be taken around the same time every day and the appropriateness of the once-a-day dosing should be re-assessed regularly.

For treating men with benign prostatic hyperplasia, or men with both benign prostatic hyperplasia and erectile dysfunction, the recommended dose is 5 mg once a day.Patients with severe liver problems or kidney problems should not take more than 10 mg in one dose.Once-a-day dosing is not recommended in patients with severe kidney problems, and should only be prescribed to patients with liver problems after a careful evaluation of the benefits and risks of taking the medicine.

How Does Cialis Work?

The active substance of Cialis, tadalafil, belongs to a group of medicines called 'phosphodiesterase type 5 (PDE5) inhibitors'. It works by blocking the phosphodiesterase enzyme, which normally breaks down a substance known as cyclic guanosine monophosphate (cGMP). During normal sexual stimulation,cGMP is produced in the penis, where it causes the muscle in the spongy tissue of the penis (the corpora cavernosa) to relax, allowing the flow of blood into the corpora, producing the erection.

By blocking the breakdown of cGMP, Cialis restores erectile function. However, sexual stimulation is still needed. By blocking the phosphodiesterase enzyme and preventing the breakdown of cGMP, Cialis also improves the blood flow to, and relaxes the muscles of, the prostate and bladder. This may reduce the problems with the flow of urine which are symptoms of benign prostatic hyperplasia.

How Long Does Cialis Take To Work?

On average, Cialis starts to work in about 30 minutes and can take up to 2 hours to take effect.

How well a medication works depends on the individual and can vary from person to person.

Don't be discouraged if Cialis doesn't work right away. If you're nervous or anxious, this affects your arousal and ability to get or keep an erection.

Talk with a doctor about your experience with Cialis to see whether a dose increase or switching to a different ED medication would work better.

●Try different timing if you take it as needed. You may need to take Cialis a few times for you to figure out the best timing for as-needed dosing. Don't take more than one dose in a day.

●Be consistent for daily use. Some people prefer the daily dose because it allows small amounts of Cialis to always be in your bloodstream, so you can have flexibility with sexual activity. For the daily dose, try to take it at the same time every day.

How Much Tadalafil (Cialis) Can I Take In A Day?

Take tadalafil (Cialis) as prescribed by your provider. If you're taking tadalafil (Cialis) as-needed for ED, you should take no more than one dose per day. The effects of tadalafil (Cialis) should last for up to 36 hours after a dose. Taking this medication more often can raise your risk for serious side effects, such as priapism or vision changes. If you have questions about your dose of tadalafil (Cialis), talk to your provider.

How long does tadalafil (Cialis) last?

Tadalafil (Cialis) can work for up to 36 hours after you take it. But this doesn't mean that the erection will last the entire time. It just means that you might be able to achieve more than one erection within this time frame without having to take another dose of tadalafil (Cialis). But if an erection lasts for longer than 4 hours, seek emergency medical care as this can lead to permanent damage to the penis.

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