TB-500 is a synthetic version of the naturally occurring peptide thymosin beta-4, aka timbetasin. Research on TB-500 usually refers to it as synthetic thymosin beta-4.
Thymosin beta-4 is found in every cell in the human body except erythrocytes, and is thought to play a role in angiogenesis, wound healing, and cell proliferation, differentiation, and migration.
TB-500 is nonetheless under active research for its potential effects on cell migration and tissue repair, formation of new blood vessels, maturation of stem cells, survival of various cell types, and anti-inflammatory action.
Yet, a naturally occurring fragment of thymosin beta-4, called N-acetyl seryl-aspartyl-lysyl-proline (Ac-SDKP), is an orally active peptide thought to possess similar antifibrotic, anti-inflammatory, angiogenic properties, and effects on cell migration and survival.
It has been investigated as an inhibitor of hematopoietic stem cell proliferation and a chemoprotective agent. Researchers may find the TB-500 fragment included in innovative TB-500 capsule formulas intended for tissue repair and recovery.
