AOD 9604 stimulates weight loss via mechanisms similar to HGH. The growth hormone stimulates the release of fatty acids from your adipose cells by triggering various cellular pathways.
Growth hormone affects the activity of several enzymes called lipases which prevent the fat from returning back into your adipose tissues.
HGH frag does not affect the natural HGH production and it does not act as a growth hormone secretagogue. It will not affect your hunger levels or increase your appetite.
Animal studies, comparing the effect of 250 mg/kg/day of AOD9604 and 1 mg/kg/day of HGH for 14 days report different results in lean and obese mice.
In lean mice, HGH but not AOD 9604 or placebo resulted in increased lean body mass. Thus it appears that HGH Fragment 176-191 is not effective in building muscle.
In obese mice, both HGH and AOD 9604 resulted in weight loss. The scientists reported a 40% reduction in adipose tissue in the HGH group vs 28% with AOD 9604.
Contrary to what most online sources may suggest, experiments reveal that HGH fragment 176-191 is less effective than HGH in burning fat.
Growth hormone likely burns more fat due to its effects on insulin resistance. It reduces glucose uptake which forces cells to take more fat instead. Unlike HGH, the fragment doesn't increase insulin resistance.
According to anecdotal evidence, AOD 9604 benefits may also include small improvements in cholesterol levels and insulin sensitivity.
Preliminary evidence from animal experiments showed that injecting the peptide into the joint may stimulate cartilage regeneration and connective tissue repair. However, human studies are lacking.
Currently, the peptide is studied for effectiveness in pain management under the name LAT 8881. However, preliminary results do not appear promising.
