●Obesity Trial Range: Typically started at 1.5-3.0mg weekly, titrated up every 4 weeks to doses of 4.5mg, 6mg, or 9mg weekly based on tolerance and response.
●Bodybuilding (Cutting) Theoretical Approach:
○Extreme Caution: Start very low (e.g., 0.5mg - 1.0mg weekly) to assess tolerance.
○Slow Titration: Increase by 0.5mg - 1.0mg every 2-4 weeks only if needed and tolerated.
○Effective Range (Speculative): Many report effects in the 1.5mg - 4.5mg weekly range. Higher doses (6mg, 9mg) likely amplify side effects disproportionately.
○Goal-Oriented: Use the lowest effective dose to achieve fat loss goals. Higher isn't always better due to side effects.
○Duration: Typically aligned with the cutting phase duration (e.g., 12-20 weeks). Longer use increases adaptation and side effect risks.
●"Lean Gains" Use: Highly discouraged and theoretically impractical due to appetite suppression. If attempted, doses would likely need to be minimal (<< 1mg weekly), but efficacy is dubious.






