●Duration: Cycles are typically aligned with the length of a cutting phase, often 12-20 weeks. Long-term use beyond achieving the target physique is generally discouraged due to cost, diminishing returns, potential for tolerance (tachyphylaxis to appetite effects), and unknown long-term effects in healthy individuals.
●Structure:
○Phase 1 (Initiation & Titration - Weeks 1-4): Start very low dose (e.g., 1.25mg or 2.5mg). Monitor tolerance and appetite effects closely.
○Phase 2 (Active Cutting - Weeks 5-16/18): Titrate up gradually to the lowest effective dose (e.g., 5mg - 10mg) as needed to maintain appetite control and fat loss momentum. Maintain consistent diet and training.
○Phase 3 (Taper & Discontinuation - Weeks 17/19-20+): As the goal physique is neared (1-3 weeks out), consider tapering DOWN the dose (e.g., reduce by 2.5mg) or discontinuing. This helps manage rebound hunger and gastrointestinal issues that can occur upon abrupt cessation, potentially disrupting peak week protocols. Do not introduce a new dose close to a contest.
