Clomid(Clomiphene) High Quality CAS:911-45-5

Description

Clomiphene is a selective estrogen receptor modulator (SERM) that competitively binds to estrogen receptors in the body, including the hypothalamus and pituitary gland. Estrogen normally has a negative feedback action on the hypothalamus and pituitary gland, so when the actions of estrogen on these structures are blocked, the pituitary is stimulated to increase the secretion of LH and FSH. The extra LH secreted causes the Leydig cells in the testicles to make more testosterone. If FSH levels are inappropriately low, then an increase in FSH secretion can also increase sperm production.

The ability of clomiphene to increase testosterone levels is roughly comparable to that of testosterone gels, and has the ability to increase libido, energy and sense of well-being in hypogonadal men. [Katz DJ. BJUI 2012] A long term (mean follow-up 4.5 years) study of 120 men on clomiphene noted sustained normalization of testosterone levels in 88% of men with improvement in their hypogonadal symptoms in 77%. [Krzastek SC. JUrol 2019]

Since clomiphene works by increasing LH production by the pituitary gland, if the LH is already elevated (indicating Leydig cell dysfunction), then clomiphene will not be as effective. Men who have a baseline LH of over 20 IU/L prior to starting any treatment will therefore likely not benefit from using clomiphene.

Clinical Data

How Does Clomid Work?

Clomid works by blocking the estrogen receptors on the pituitary gland. This prevents the interaction of the female sex hormone with the pituitary gland. If allowed to happen, this interaction would have reduced the production of luteinizing hormone (LH) and follicle-stimulating hormone (FSH).

Both these hormones stimulate your testicles to make testosterone. LH and FSH production will thus boost testosterone levels in your body. Together with the reduction in estrogen, this will translate to a higher testosterone/estrogen ratio.

Clomid could increase your sperm count, too. Various studies have shown that low-dose treatment with this drug improved sperm count in men experiencing low testosterone symptoms. This means you can count on Clomid to boost your sex drive/libido, too.

Keep in mind that Clomid PCT comes in handy for harsh prohormone or steroid cycles. The sort of which consist of multiple orals and/or injectables and cause severe testosterone suppression. Such cycles need an effective post cycle therapy to boost natural testosterone production.

What Is Clomid Used For?

Bodybuilders use Clomid to boost natural testosterone production being suppressed by anabolic steroid or prohormone cycle. This post cycle therapy supplement also blocks estrogen receptors in the body, helping bodybuilders suffering from 'man boobs' get rid of them.

Clomid also helps prevent water retention. It's one of the most dreaded side effects of steroid use. If left unattended, it can cause some severe health implications. Excess water retention can disfigure your physique and might also contribute to high blood pressure.
Bodybuilders also use Clomid for performance gains. Research has shown that users combining this anti-estrogen with strong weight lifting experience an increase in muscle mass. They also benefit from a reduction in body fat and an overall improvement in their physique.

All in all, Clomid PCT kills two birds with one stone. It helps prevent some of the most serious side effects of anabolic steroid cycle, including water retention and gynecomastia. And it lets you keep all the gains – increase in muscle mass, reduction in body fat – you've worked so hard to achieve in the gym.

Benefits

For people who are appropriately treated with Clomid, there are many benefits:

Can be the most cost-effectiveTrusted Source option in some cases, especially when compared with other fertility treatments such as in vitro fertilization (IVF).

It is an oral medication, which makes it less invasive than other treatments.

It can be prescribed by your OB-GYN or primary care provider, so you do not need to see a reproductive specialist.

There are relativelyTrusted Source few side effects, and many of the possible ones are rare, so Clomid is generally well-tolerated by females who take it.

FAQ

What do I do if Clomid doesn't work?

If you don't become pregnant after three to six cycles of Clomid (or however many your doctor recommends), it may be time to see a fertility specialist and move on to more aggressive treatment.

What is ovulation?

Ovulation is the process of releasing an unfertilized egg from the ovary each month, usually around the 14th day of a female's menstrual cycle. Without regular ovulation, it can become difficult to get pregnant. This is because it's difficult to figure out when to have intercourse so that the egg and sperm will meet at the right time.

Learn more about ovulation.

Can Clomid be used for male infertility?

Clomid is only approved by the Food and Drug Administration (FDA) for treating females. However, doctors may prescribe it off-label to treat male infertility and secondary hypogonadism. In males, Clomid can help induce the production of sperm.

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