What is Arimidex?
Arimidex lowers estrogen levels in postmenopausal women, which may slow the growth of certain types of breast tumors that need estrogen to grow in the body.
Arimidex is used to treat breast cancer in postmenopausal women.
Arimidex is often given to women whose cancer has progressed even after taking tamoxifen (Nolvadex, Soltamox).
Warnings
Arimidex may decrease blood flow to your heart, especially if you have ever had coronary artery disease (clogged arteries). Seek medical attention if you have new or worsening chest pain, or if you feel short of breath.
Do not use anastrozole if you are pregnant. It could harm the unborn baby.
Arimidex may not work as well if you take it together with estrogen medication (such as hormone replacement therapy, estrogen creams, or birth control pills, injections, implants, skin patches, and vaginal rings).
Arimidex may increase your risk of a stroke or blood clot. Call your doctor at once if you have sudden numbness or weakness, (especially on one side of the body), sudden severe headache, slurred speech, or problems with vision or balance.
Before taking this medicine
You should not use Arimidex if you are allergic to anastrozole, or if you have not yet completed menopause.
Arimidex is not approved for use in men or children.
You should not take anastrozole if you also take tamoxifen.
To make sure this medicine is safe for you, tell your doctor if you have ever had:
heart problems;
coronary artery disease (clogged artery disease);
high cholesterol; or
osteoporosis or low bone mineral density.
Hormonal cancer treatment can weaken your bones. You may be more likely to have a broken bone while using Arimidex. Talk with your doctor about ways to keep your bones healthy.
Although it is not likely that a postmenopausal woman would be pregnant, anastrozole may harm an unborn baby. You may need to have a negative pregnancy test before starting this treatment. Use effective birth control if you are not past menopause. Keep using birth control for at least 3 weeks after your last dose of Arimidex. Tell your doctor if you become pregnant.
How should I take Arimidex?
Take Arimidex exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.
Arimidex is usually taken once per day. Follow your doctor's dosing instructions very carefully.
You may take Arimidex with or without food.
You may need to keep taking this medication for up to 5 years. Follow your doctor's instructions.
Store at room temperature away from moisture and heat.
Important Safety Information About ARIMIDEX
Prescription ARIMIDEX is only for postmenopausal women. ARIMIDEX should not be taken if you are pregnant because it may harm your unborn child. Do not take ARIMIDEX if you are allergic to any of its ingredients
Based on information from a study in patients with early breast cancer, women with a history of blockages in heart arteries (ischemic heart disease) who take ARIMIDEX may have a slight increase in this type of heart disease compared to similar patients who take tamoxifen
ARIMIDEX can cause bone softening/weakening (osteoporosis) increasing the chance of fractures. In a clinical study in early breast cancer, there were more fractures (including fractures of the spine, hip, and wrist) with ARIMIDEX (10%) than with tamoxifen (7%)
In a clinical study in early breast cancer, some patients taking ARIMIDEX had an increase in cholesterol. Skin reactions, allergic reactions, and changes in blood tests of liver function have also been reported
In the early breast cancer clinical trial, the most common side effects seen with ARIMIDEX include hot flashes, joint symptoms (including arthritis and arthralgia), weakness, mood changes, pain, back pain, sore throat, nausea and vomiting, rash, depression, high blood pressure, osteoporosis, fractures, swelling of arms/legs, insomnia, and headache
In advanced breast cancer trials, the most common side effects seen with ARIMIDEX versus tamoxifen include hot flashes, nausea, decreased energy and weakness, pain, back pain, headache, bone pain, increased cough, shortness of breath, sore throat, and swelling of arms and legs. Joint pain/stiffness has been reported in association with the use of ARIMIDEX
ARIMIDEX should not be taken with tamoxifen or estrogen-containing therapies
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