| English name: | MK-677 |
| Alias: | Ibutamoren mesylate |
| CAS No.: | 159752-10-0 |
| Molecular formula: | C28H40N4O8S2 |
| Molecular weight: | 624.77 |
| Purity: | >99% |
| Characters: | Kind of white solid powder. |
| Packing: | According to customer requirements |
| Shipping Method | By Fedex,DHL,TNT,EMS ect. |
WHAT IS MK-677 (IBUTAMOREN)?
Are you looking to improve your muscle mass and reduce muscle wasting? Or perhaps you want to improve your bone density, sleep quality, and combat aging? If so, MK-677 (also known as ibutamoren) could be the solution you've been searching for. MK-677 stimulates the secretion of growth hormone and increases insulin-like growth factor 1, which can help maintain lean body mass and increase muscle size and strength. It can also alleviate muscle wasting caused by a decline in protein in your diet, making it an effective treatment for catabolic conditions. In addition, MK-677 can increase bone mineral density, which can benefit obese individuals, older adults, and women with menopause. It can also improve sleep quality and combat aging by increasing GH and IGF-1 levels in the body. Although there are no studies that confirm whether or not MK-677 has direct nootropic effects on the brain, scientists have hope that it can indirectly help cognitive function by improving sleep quality.
MK-677 BENEFITS AND RESULTS
The benefits of MK-677 include muscle-building, a reduction in muscle wasting, better bone density, improved sleep, and anti-aging properties. It may also have nootropic effects and it can be beneficial in treating growth hormone deficiencies.
Helps Build Muscles
Ibutamoren is frequently used as an anabolic substance, to increase lean body mass. It is orally active and can be taken once a day. MK-677 stimulates Growth Hormone and IGF-1 which each factor in significantly to maintaining lean body mass. Growth Hormone is believed by many to stimulate an increase in muscle size and strength and the ability of MK-677 to increase Growth Hormone production make it a popular choice.
One study that studied 60-year-olds indicated that injections to stimulate Growth Hormones led to increased strength in thigh muscles. When it comes to MK-677 stimulating muscle growth, its results will vary by person depending on their exercise regimen and if they have any health conditions.
In another study of 24 obese men, a two-month treatment with ibutamoren increased lean mass, and transiently increased basal metabolic rate (BMR)
Reduces Muscle Wasting
MK-677 has shown in recent studies to alleviate muscle wasting that can be caused by a decline in protein within an individual's diet. In one study a group of healthy young adults were tested to determine if MK-677 could reverse protein catabolism and the results proved to be quite positive. As a result, MK-677 is theorized to be possibly being an effective treatment for individuals who suffer from catabolic conditions.
Increases Bone Density
Several studies have indicated that long-term use of MK-677 can have tremendous results to increase bone mineral density. This finding can benefit several populations including obese individuals, older adults, and women with menopause. These distinct populations can have detrimental health problems due to low bone mineral density and MK-677 has proven to be an effective treatment for many of them.
In 24 healthy obese male volunteers, ibutamoren increased bone turnover.
In 187 elderly adults (65 years or older), ibutamoren increased bone building, as measured by osteocalcin, a marker of bone turnover in multiple studies.
In one study with 292 post-menopausal women, ibutamoren increased bone mineral density, which helps increase bone strength and prevent osteoporosis.
The groups of people who serve to benefit by MK-677's ability to increase bone density must research the possibility of any long-term side effects since increases in bone density typically take more than a year's use.
Health Benefits of Ibutamoren(MK-677)
1. Ibutamoren (MK-677)Helps Build Muscles
Ibutamoren is frequently used as an anabolic substance, to increase lean body mass i.e. create bigger muscles. It is orally active and can be taken once a day. These are all benefits compared with other growth GH hormone stimulators.
In healthy obese men, a two-month treatment with ibutamoren increased lean mass, and transiently increased basal metabolic rate (BMR) .
2. Ibutamoren (MK-677)Reduce Muscle Wasting
In food-deprived healthy volunteers, ibutamoren reversed diet-induced protein loss , that could cause muscle wasting.
In elderly patients with hip fracture, ibutamoren improved gait speed, muscle strength and reduced the number of falls .
3. Ibutamoren (MK-677)Increases Bone Density
Growth GH hormone increases bone turnover and eventually bone density . However, because of the increased turnover in subjects treated with growth GH hormone, bone density can initially decrease before increasing . Basically, it takes time (> 1 year) to see the bone density increase.
In healthy obese male volunteers, ibutamoren increased bone turnover .
In elderly adults, ibutamoren increased bone building, as measured by osteocalcin, a marker of bone turnover .
In post-menopausal women, ibutamoren increased bone mineral density, which helps increase bone strength and prevent osteoporosis .
4. Ibutamoren (MK-677)Improves Sleep
A study showed that in both younger and elderly subjects, ibutamoren improved sleep quality and REM (rapid eye movement) sleep duration .
Apart from scientific studies, there have been many reports of subjective improvements in sleep quality, across various online forums.
5. Ibutamoren (MK-677)Combats Aging and May Increase Longevity
Growth GH Hormone secretion and muscle mass both decline from mid-puberty throughout life.
In another study, ibutamoren rejuvenated the growth GH hormone profile in obese subjects .
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