Description
Mesterolone, sold under the brand name Proviron among others, is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of low testosterone levels. It has also been used to treat male infertility, although this use is controversial. It is taken by mouth.
Mesterolone, also known by its brand name Proviron, is an orally active synthetic androgen and derivative of dihydrotestosterone (DHT). It is primarily used in the medical field for the treatment of conditions related to low testosterone levels.
Mesterolone is prescribed to men who have low testosterone levels, which can occur due to various factors such as hypogonadism or infertility. It works by supplementing the body with androgens, which are the male sex hormones, to restore normal testosterone levels. This can help improve symptoms such as low libido, erectile dysfunction, and fatigue associated with low testosterone.
Unlike many other anabolic steroids, mesterolone does not have strong anabolic effects, meaning it does not promote significant muscle growth. It is instead known for its anti-estrogenic properties. Mesterolone binds to the aromatase enzyme, inhibiting the conversion of testosterone into estrogen. This can be beneficial in preventing or reducing estrogen-related side effects, such as water retention and gynecomastia (enlargement of breast tissue in males), that can occur with the use of other steroids.
Mesterolone is generally well-tolerated when used as prescribed under medical supervision. However, it may still have potential side effects, including changes in mood, acne, oily skin, hair loss (in individuals predisposed to male pattern baldness), and suppression of natural testosterone production when used for extended periods. It is important to follow the prescribed dosage and duration of use to minimize these risks.
1) Mesterolone has a strong affinity for sex hormone binding globulin (SHBG). It increases the amount of circulating free testosterone by combining with SHBG, thus improving the testosterone level.
2) Mesterolone has been 5 α- Restore, it is not 5 α- The substrate of reductase, so it has no enhancement effect in skin, hair follicle, prostate and other tissues
3) Aromatase is also called estrogen synthetase, which is the key enzyme of estrogen biosynthesis. Mesterolone is not the substrate of aromatase, so it cannot be converted into estrogen. Estrogen can cause breast development and fluid retention in men.
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