High Purity Anti Estrogen Steroids Toremifene Citrate CAS 89778-27-8

CAS:89778-27-8

MF:C32H36ClNO8

MW:598.08

Synonyms:(z)-4-chloro-1,2-diphenyl-1-(4-(2-(n,n-dimethylamino)ethoxy)phenyl)-1-butene ;2-(4-(4-chloro-1,2-diphenyl-1-butenyl)phenoxy)-n,n-dimethyl-ethanamin(z)-ethanamin ;2-hydroxy-1,2,3-propanetricarboxylate(1:1) ;fareston ;fc1157a ;nk622 ;TOREMIFENE CITRATE;(z)-2-[4-(4-chloro-1,2-diphenyl-1-butenyl)phenoxy]-n,n-dimethyl-ethanamine 2-hydroxy-1,2,3-propanetricarboxylate

Melting point:160-162°C

Boiling point:146-148C

Density 1,045g/cm

refractive index 1,416-1,418

storage temp. -20°C Freezer

solubility DMSO: >10mg/mL

color white to off-white

Merck 14,9550

Symbol(GHS)

What is Tamoxifen Citrate?

Tamoxifen citrate is a medication commonly used to treat breast cancer. It is classified as a selective estrogen receptor modulator (SERM). This drug works by blocking estrogen receptors in breast tissue, which can inhibit the growth of estrogen receptor-positive breast cancer cells.

Many breast cancer tumors are estrogen receptor-positive, meaning that they require estrogen to grow. By preventing estrogen from stimulating these cancer cells, tamoxifen helps to slow or stop the progression of the cancer.

Tamoxifen is typically prescribed for both premenopausal and postmenopausal women diagnosed with hormone receptor-positive breast cancer. It is usually taken orally in tablet form once a day, and the course of treatment may last for several years, depending on the individual case. Additionally, tamoxifen may also be used in women at high risk of breast cancer as a preventive measure.

However, tamoxifen can cause side effects, including hot flashes, vaginal dryness, mood changes, and an increased risk of blood clots and uterine cancer. It's essential to discuss the benefits and risks with a healthcare provider before starting tamoxifen therapy.

Is Toremifene Citrate the Same as Tamoxifen Citrate?

While both toremifene citrate and tamoxifen citrate belong to the same class of drugs-selective estrogen receptor modulators (SERMs)-they are not identical medications. Both drugs work by blocking estrogen's effects on the breast tissue, thus preventing estrogen receptor-positive breast cancer cells from growing.

However, there are some key differences between the two drugs:

Toremifene has a higher affinity for estrogen receptors than tamoxifen, which can lead to a stronger anti-estrogen effect in certain tissues.

Toremifene also has a longer half-life, meaning it stays in the body for a longer period, which may make it more convenient for some patients.

Toremifene is often prescribed when tamoxifen is not well tolerated or is ineffective in a patient.

While both medications are effective for treating breast cancer, they may have different side effects and interactions. Your healthcare provider can help determine which medication is best for your specific case.

What Class of Drug is Toremifene?

Toremifene belongs to the class of drugs known as selective estrogen receptor modulators (SERMs). These drugs interact with estrogen receptors in various tissues and can either block estrogen's effects (antagonistic) or mimic estrogen's effects (agonistic), depending on the tissue type.

In breast tissue, toremifene acts as an estrogen antagonist, blocking estrogen and preventing the growth of estrogen receptor-positive breast cancer cells. However, in other tissues like bones, toremifene may act as an estrogen agonist, helping to maintain bone density.

Product Information for Reference:

Place of Origin: China

Certifications: ISO9001:2008, KOSHER, GMP, SGS

Quality Standard: USP

Minimum Order Quantity: 10 g

Production Capacity: 1000 Kg/Month

Package & Delivery:

Packaging Options: Foil bag, Foil tin, Drum, or custom requests

Payment Methods: T/T, Western Union

Shipping Methods: EMS, DHL, FedEx, UPS

Lead Time: Within 48 hours after confirming payment

Delivery Time: Within 7 working days after confirming payment

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