1.Tesamorelin Basic information.
CAS:218949-48-5
Sequence (three letter code): trans-3-hexenyl-tyr-ala-asp-ala-ile-phe-thr-asn-ser-tyr-arg-lys-val-leu-gly-gln-leu-ser-met-ser-arg-gln-gly-glu-ser-met-ser-arg-gln-gly-glu-ser-asn-gln-gly-ala-arg-leu-nh a pair of
Purity: ninety nine
Specification: 2mg/vial
Appearance: White freeze-dried Powder
Method of Analysis: HPLC
Storage: freeze-dried peptides though stable at temperature for three months, ought to be keep desiccated below -18° C. Upon reconstitution of the amide it ought to be keep at 4° C between 2-21 days and for future use below -18° C.
2.What is Tesamorelin?
Tesamorelin, (formerly called TH9507), may be a form of amide referred to as a hormone-releasing issue (GHRF). internal secretion-releasing factor|GHRF|releasing factor|releasing hormone|RF} causes hormone to be created and unfold within the body, that helps increase metabolism, cut back belly fat, improve body form, and use of energy. Tesamorelin (formerly called TH9507) may be a artificial growth hormone-releasing issue that stimulates the pituitary body within the brain to secrete hormone; this indirect approach seems to keep up a lot of stable, natural levels, like CJC-1295 DAC,. Clinical trials have shown that tesamorelin considerably reduces abdominal fat with fewer facet effects than human human growth hormone itself, though abdominal fat could come back when the Tesamorlein is interrupted (depending upon the individual). Tesamorelin has been shown to cut back lipodystrophy in HIV-infected people moreover as equally reducing abdominal fat in NON-HIV-Infected people.
3.Tesamorelin Applications
Treatment of HIV-associated lipodystrophy: Lipodystrophy is a common side effect of long-term antiretroviral therapy in people living with HIV. It can involve the loss of subcutaneous fat in certain areas (lipoatrophy) and the accumulation of visceral fat in the abdomen (lipohypertrophy). Tesamorelin is administered by subcutaneous injection and has been shown to specifically target and reduce abdominal fat, which can improve the overall body composition and metabolic health of individuals with HIV-related lipodystrophy.
4.The impact of Tesamorelin
The main impact of Tesamorelin is its ability to stimulate the production and release of growth hormone from the pituitary gland. This, in turn, helps to increase insulin-like growth factor 1 (IGF-1) levels, leading to a reduction of visceral adipose tissue (abdominal fat). The specific benefits of Tesamorelin include:
Reduction in abdominal fat: Clinical trials have shown that Tesamorelin can significantly reduce visceral adipose tissue, leading to improved body composition and reduced abdominal circumference.
Metabolic improvements: By reducing visceral fat, Tesamorelin can improve insulin sensitivity and lipid profiles, potentially reducing the risk of metabolic complications such as insulin resistance, dyslipidemia, and cardiovascular disease.
Improved quality of life: Lipodystrophy can be distressing for individuals, and the reduction in abdominal fat and other associated improvements may lead to an enhanced quality of life.
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