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Description
PT141, also known by its scientific name Bremelanotide, is a synthetic peptide that has recently gained significant attention due to its ability to enhance sexual health. Originally developed as a tanning agent, PT141's unexpected effects on sexual arousal and libido led to its use as a treatment for sexual dysfunction.
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What is PT141 Powder?
PT141 powder is the powdered form of Bremelanotide, a melanocortin receptor agonist that specifically targets the central nervous system (CNS) to enhance sexual arousal and libido. Unlike many traditional erectile dysfunction (ED) medications, which primarily affect the vascular system, PT141 acts on the brain to stimulate sexual desire. This makes it a unique and effective option for individuals dealing with sexual dysfunction caused by neurological or psychological factors.
The powder form is typically reconstituted with sterile water or bacteriostatic water for subcutaneous injection or in some cases, it may be used for nasal administration. The peptide is known for its effects on melanocortin receptors, especially the MC4 receptor, which is critical in the regulation of sexual behavior.
Clinical Data
Trade names
Bremelanotide, Vyleesi, Rekynda, bremelanotide acetate CAS
189691-06-3
Molar mass
1025.182
Formula
C50H68N14O10 Purity
Above 98%
Apprarance
White crystalline powder Physical and Chemical Characteristics
Appearance
White to off-white lyophilized powder
Uniform texture, ideal for accurate laboratory preparation
Purity
Typically available at ≥98% purity, suitable for controlled experimental environments
Stability
Lyophilized state enhances long-term stability
Designed for reliable reconstitution with compatible research-grade solvents
Key Advantages
1. High Purity and Consistency
Each production batch is synthesized under strict quality standards to ensure reproducibility across research applications.
2. Strong Structural Stability
The packaged peptide maintains its integrity during storage and transport, supporting dependable scientific analysis.
3. Broad Research Relevance
PT-141 is frequently used in studies involving:
Melanocortin receptor pathways
Neurochemical signaling mechanisms
Behavioral and central nervous system model exploration
4. Convenient Laboratory Handling
The freeze-dried powder format provides flexibility during solution preparation and enables controlled experimental design.
Research Applications
PT-141 is primarily used in research associated with:
● Melanocortin Receptor Activity
Useful for exploring MC3R and MC4R receptor interactions and downstream physiological responses.
● Neurobiological Investigations
Assists in studying neural pathways linked to behavior, hormonal signaling, and central modulation.
● Peptide Structure–Function Studies
Commonly utilized in labs examining relationships between peptide sequences and receptor affinity.
Dosage and Administration of PT141 Powder
The dosage of PT141 varies based on the individual's condition and the method of administration. The powdered form of PT141 must first be reconstituted with sterile water or bacteriostatic water before use.
Recommended Dosage:
●For Men: The typical dosage for men is between 1 to 2 mg per dose, administered via subcutaneous injection approximately 30–60 minutes before sexual activity.
●For Women: The typical dosage for women is between 0.5 to 1 mg, also injected 30–60 minutes before sexual activity. Women may require a lower dose due to differences in physiology and hormone levels.
Reconstitution:
●To reconstitute PT141 powder, the user should mix it with sterile water or bacteriostatic water. The concentration will vary depending on the specific brand, but a general guideline is to add 1 mL of water to a vial containing 5 mg of PT141 to achieve a concentration of 5 mg/mL.
Administration:
●After reconstitution, PT141 is administered through subcutaneous injections, which are typically performed in the lower abdomen or thigh areas. Injections should be done 30–60 minutes before sexual activity to allow the compound time to take effect.
Storage Recommendations
Store at 2–8°C for short-term stability
For extended storage, keep at –20°C
Keep sealed, avoid moisture, and minimize repeated freeze–thaw cycles
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