Peptides Liraglutide 2mg/vial

Description

Liraglutide is a versatile and highly effective therapeutic peptide for managing diabetes, promoting weight loss, and improving overall cardiometabolic health. Its unique ability to address multiple aspects of metabolic syndrome makes it a cornerstone in modern medicine. When used correctly and in conjunction with lifestyle changes, Liraglutide offers sustainable, transformative benefits, underscoring its value as a groundbreaking pharmaceutical agent.

What is Liraglutide?

Liraglutide is a GLP-1 analog that mimics the action of the body's natural incretin hormones. It enhances glucose-dependent insulin secretion, suppresses glucagon release, and slows gastric emptying. These mechanisms combine to regulate blood sugar levels, reduce appetite, and aid in weight management.

Chemical Composition

●Molecular Formula: C172H265N43O51

●Molecular Weight: 3751.2 g/mol

●CAS Number: 204656-20-2

Key Features

●Modified for prolonged activity, allowing for once-daily administration.

●Shares 97% homology with endogenous human GLP-1.

●Stabilized against enzymatic degradation by dipeptidyl peptidase-4 (DPP-4).

Features of Liraglutide

2.1 Long-Acting Design

Liraglutide's molecular modifications extend its half-life compared to native GLP-1, making it effective for 24-hour glucose control with a single injection.

2.2 Appetite Suppression

By interacting with receptors in the brain's hypothalamus, Liraglutide significantly reduces hunger, aiding weight loss efforts.

2.3 Cardiovascular Benefits

Clinical trials have demonstrated its ability to lower cardiovascular risk by improving blood pressure, reducing arterial inflammation, and decreasing cholesterol levels.

2.4 Enhanced Insulin Sensitivity

Liraglutide improves insulin action at target tissues, aiding individuals with insulin resistance.

2.5 Multifaceted Metabolic Action

It addresses multiple facets of metabolic syndrome, including obesity, dyslipidemia, and hyperglycemia.

Is liraglutide used for weight loss?

Yes, liraglutide is used for weight loss. In 2014, it was approved for chronic weight management in adults, and in 2020, the U.S. Food & Drug Administration approved liraglutide for weight management for people aged 12 and older who have obesity.

For adolescents, obesity is defined as weighing more than 60 kg (132 pounds) and having a weight corresponding to a BMI of 30 kg/m2 or higher for adults. Liraglutide should be used to supplement a reduced-calorie, nutritious diet and plans to incorporate daily physical activity into your schedule.

Is liraglutide the same as insulin?

No, liraglutide is not the same as insulin. Insulin is used to replace natural insulin produced by the pancreas. Insulin treatment is more commonly used for people who have type 1 diabetes mellitus, a condition that typically presents in childhood. Unlike type 2 diabetes, type 1 diabetes is not associated with obesity.

You should not take liraglutide with insulin unless specifically advised to do so by your doctor because they both can cause low blood sugar. However, in some cases, liraglutide is prescribed as an add-on therapy to insulin for better glucose control for people with type 2 diabetes.

Dosage and Administration

5.1 General Guidelines

Liraglutide is administered via subcutaneous injection in areas like the abdomen, thigh, or upper arm. It can be taken at any time of day, but consistency is advised.

5.2 Dosage for Specific Applications

●Type 2 Diabetes (Victoza):

●Initial Dose: 0.6 mg daily for the first week.

●Maintenance Dose: 1.2 mg daily, with the possibility of increasing to 1.8 mg based on response.

●Weight Loss (Saxenda):

●Initial Dose: 0.6 mg daily, increasing weekly by 0.6 mg until reaching the target dose of 3.0 mg.

5.3 Monitoring

Regular monitoring of blood sugar levels, kidney function, and weight is recommended to optimize treatment.

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